Postgrad Med. 1987 Oct;82(5):225-9, 232.

Adverse effects of immunization. Is prevention possible?


Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.


Vaccination rates must be kept high to prevent epidemics of infectious disease. At the same time, parents must be informed of the rare possibility of serious adverse effects, including seizure and allergic reaction. Every physician who administers vaccine therefore needs to become familiar with the reactions that may occur with each immunologic agent used. The best safeguard against litigation, when and if a serious reaction follows vaccination, is the indication that these considerations were discussed and that an informed choice was made.